San Francisco Giants

The defending champs—and winners of two of the past three titles—look like they’re prime for another deep run into the playoffs.

They’ve officially handed the closer’s role over to Sergio Romo, who replaced the fun-loving Brian Wilson last season after Wilson’s injury, and the rotation includes stud Matt Cain and Madison Baumgartner.

The biggest question marks for the Giants are Tim Lincecum and their health. If those two improve, they may just keep the World Series trophy chilling by the Bay again.